NucPred on Proteomes

Authors: Andrea Krings, Amine Heddad, Markus Brameier and Bob MacCallum, Stockholm Bioinformatics Center, Stockholm University, Sweden.

NucPred - predictions for eukaryotic proteomes

Species:

Note: All filters/tests are combined with AND unless otherwise stated

Show only the proteins with links to database(s):
OMIM - human disease genes
PDB - protein 3D structure
( AND OR combination )

Annotation filters (can be slow! - Perl regexps allowed: e.g. nucleus|nucleolus)

UniProt ID (e.g. "PK3B_")
UniProt description (e.g. "kinase")
UniProt subcellular location
AND
UniProt GO component
AND
AND the
AND the

Only show proteins where the PredictNLS prediction is:

positive
negative

Only show proteins where the PSORT II predicted location

is is not

Click here: to filter by NucPred score

exclude all transmembrane proteins predicted by TMHMM
don't exclude lone N-terminal predicted transmembrane helices
(these could be signal peptides)

export all ACs and IDs as text file

Show proteins (ordered by NucPred score ) from to (currently 98716 matches)

You can bookmark/save your search criteria with this link. You can also start again with default settings.

UniProt accession	UniProt ID	UniProt description	NucPred score	Predict- NLS	PSORT II	TMHMM #helices	UniProt annotation for subcellular location	Uniprot GO cellular component	OMIM	PDB	sequence length
Q9Y585 UniProt NPD GO	OR1A2_HUMAN	Olfactory receptor 1A2 (Olfactory receptor 17-6) (OR17-6) (Olfactory receptor OR17-10)	0.02	-	end	7 *	Membrane; multi-pass membrane protein	integral to membrane [NAS]			309
Q9TUA8 UniProt NPD GO	OR1D2_PANTR	Olfactory receptor 1D2	0.02	-	end	7 *	Membrane; multi-pass membrane protein				312
P34982 UniProt NPD GO	OR1D2_HUMAN	Olfactory receptor 1D2 (Olfactory receptor-like protein HGMP07E) (Olfactory receptor 17-4) (OR17-4)	0.02	-	end	7 *	Membrane; multi-pass membrane protein	integral to plasma membrane [TAS]	164342		312
P58170 UniProt NPD GO	OR1D5_HUMAN	Olfactory receptor 1D5 (Olfactory receptor 17-31) (OR17-31)	0.02	-	end	8 *	Membrane; multi-pass membrane protein				312
O43749 UniProt NPD GO	OR1F1_HUMAN	Olfactory receptor 1F1 (Olfactory receptor 16-35) (OR16-35) (Olfactory receptor OR16-4)	0.02	-	end	7 *	Membrane; multi-pass membrane protein		603232		312
Q8NH92 UniProt NPD GO	OR1S1_HUMAN	Olfactory receptor 1S1	0.02	-	end	6 *	Membrane; multi-pass membrane protein				312
Q8NGQ3 UniProt NPD GO	OR1S2_HUMAN	Olfactory receptor 1S2	0.02	-	end	6 *	Membrane; multi-pass membrane protein				312
Q8NGT1 UniProt NPD GO	OR2K1_HUMAN	Olfactory receptor 2K2 (HTPCRH06)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				316
Q8NH04 UniProt NPD GO	O2T27_HUMAN	Olfactory receptor 2T27 (Olfactory receptor OR1-67)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				317
P47893 UniProt NPD GO	OR3A2_HUMAN	Olfactory receptor 3A2 (Olfactory receptor 17-228) (OR17-228)	0.02	-	end	5 *	Membrane; multi-pass membrane protein	integral to plasma membrane [TAS]			315
Q9TUA0 UniProt NPD GO	OR3A3_PANTR	Olfactory receptor 3A3	0.02	-	end	7 *	Membrane; multi-pass membrane protein				315
Q8VFD0 UniProt NPD GO	OL486_MOUSE	Olfactory receptor 486 (Olfactory receptor 204-19)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				314
Q8VG02 UniProt NPD GO	OL488_MOUSE	Olfactory receptor 488 (Olfactory receptor 204-15)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				314
Q8VEW5 UniProt NPD GO	OL493_MOUSE	Olfactory receptor 493 (Olfactory receptor 204-35)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				314
Q8VF12 UniProt NPD GO	OL495_MOUSE	Olfactory receptor 495 (Olfactory receptor 204-37)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				330
Q8VEW2 UniProt NPD GO	OL498_MOUSE	Olfactory receptor 498 (Olfactory receptor 204-36)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				330
Q8NGN8 UniProt NPD GO	OR4A4_HUMAN	Olfactory receptor 4A4 (Olfactory receptor OR11-107)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				299
Q8NGP0 UniProt NPD GO	OR4CD_HUMAN	Olfactory receptor 4C13 (Olfactory receptor OR11-260)	0.02	-	end	6 *	Membrane; multi-pass membrane protein				309
Q8NGL9 UniProt NPD GO	OR4CG_HUMAN	Olfactory receptor 4C16 (Olfactory receptor OR11-135)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				310
Q8NH37 UniProt NPD GO	OR4C3_HUMAN	Olfactory receptor 4C3 (Olfactory receptor OR11-98)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				302
Q8NGB8 UniProt NPD GO	O4F15_HUMAN	Olfactory receptor 4F15	0.02	-	end	7 *	Membrane; multi-pass membrane protein				312
Q8NGD4 UniProt NPD GO	OR4K1_HUMAN	Olfactory receptor 4K1	0.02	-	end	7 *	Membrane; multi-pass membrane protein				311
Q8NGD5 UniProt NPD GO	OR4KE_HUMAN	Olfactory receptor 4K14 (Olfactory receptor OR14-22)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				310
Q8N0Y3 UniProt NPD GO	OR4N4_HUMAN	Olfactory receptor 4N4	0.02	-	end	7 *	Membrane; multi-pass membrane protein				316
Q60889 UniProt NPD GO	OLF5_MOUSE	Olfactory receptor 5 (Olfactory receptor 103-8) (Odorant receptor M41)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				312
Q8NGJ7 UniProt NPD GO	O51A2_HUMAN	Olfactory receptor 51A2	0.02	-	end	7 *	Membrane; multi-pass membrane protein				313
Q9Y5P0 UniProt NPD GO	O51B4_HUMAN	Olfactory receptor 51B4 (Odorant receptor HOR5'beta1)	0.02	-	end	7 *	Membrane; multi-pass membrane protein	integral to membrane [NAS]			310
Q8NGK4 UniProt NPD GO	O52K1_HUMAN	Olfactory receptor 52K1	0.02	-	end	7 *	Membrane; multi-pass membrane protein				314
Q8NHC6 UniProt NPD GO	O5AV1_HUMAN	Olfactory receptor 5AV1	0.02	-	end	7 *	Membrane; multi-pass membrane protein				308
Q96R09 UniProt NPD GO	OR5B2_HUMAN	Olfactory receptor 5B2 (OST073) (Olfactory receptor OR11-240)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				309
Q8NHB7 UniProt NPD GO	OR5K1_HUMAN	Olfactory receptor 5K1 (HTPCRX10)	0.02	-	end	5 *	Membrane; multi-pass membrane protein				316
Q96RB7 UniProt NPD GO	OR5MB_HUMAN	Olfactory receptor 5M11	0.02	-	end	7 *	Membrane; multi-pass membrane protein				305
Q8NH85 UniProt NPD GO	OR5R1_HUMAN	Olfactory receptor 5R1 (Olfactory receptor OR11-185)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				324
Q8NGG2 UniProt NPD GO	OR5T2_HUMAN	Olfactory receptor 5T2	0.02	-	end	7 *	Membrane; multi-pass membrane protein				329
Q8VBW9 UniProt NPD GO	OLF63_MOUSE	Olfactory receptor 63 (Olfactory receptor 267-1) (Odorant receptor M4)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				316
O95007 UniProt NPD GO	OR6B1_HUMAN	Olfactory receptor 6B1 (Olfactory receptor 7-3) (OR7-3)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				311
Q8NGX8 UniProt NPD GO	OR6Y1_HUMAN	Olfactory receptor 6Y1 (Olfactory receptor OR1-11)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				325
Q8NGA0 UniProt NPD GO	OR7G1_HUMAN	Olfactory receptor 7G1 (Olfactory receptor 19-15) (OR19-15)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				333
Q8NGG7 UniProt NPD GO	OR8A1_HUMAN	Olfactory receptor 8A1 (OST025)	0.02	-	end	6 *	Membrane; multi-pass membrane protein				309
Q8NGG6 UniProt NPD GO	OR8BC_HUMAN	Olfactory receptor 8B12 (Olfactory receptor OR11-317)	0.02	-	end	7 *	Membrane; multi-pass membrane protein				310
Q96RD0 UniProt NPD GO	OR8B2_HUMAN	Olfactory receptor 8B2	0.02	-	end	8 *	Membrane; multi-pass membrane protein				313
Q8NGG8 UniProt NPD GO	OR8B3_HUMAN	Olfactory receptor 8B3	0.02	-	end	8 *	Membrane; multi-pass membrane protein				313
Q15614 UniProt NPD GO	OR8G2_HUMAN	Olfactory receptor 8G2 (Olfactory receptor TPCR120) (Olfactory receptor OR11-297)	0.02	-	end	8 *	Membrane; multi-pass membrane protein	integral to membrane [NAS]			310
Q8NGG5 UniProt NPD GO	OR8K1_HUMAN	Olfactory receptor 8K1	0.02	-	end	8 *	Membrane; multi-pass membrane protein				319
Q8NH10 UniProt NPD GO	OR8U1_HUMAN	Olfactory receptor 8U1	0.02	-	end	7 *	Membrane; multi-pass membrane protein				309
Q8NGQ1 UniProt NPD GO	OR9G4_HUMAN	Olfactory receptor 9G4	0.02	-	end	7 *	Membrane; multi-pass membrane protein				312
P37070 UniProt NPD GO	OLF4_CHICK	Olfactory receptor-like protein COR4	0.02	-	end	5 *	Membrane; multi-pass membrane protein				312
Q26419 UniProt NPD GO	OLF1_APILI	Olfactory receptor-like protein HbA1 (Fragment)	0.02	-	nuc	3 *	Membrane; multi-pass membrane protein (Probable)				165
Q26420 UniProt NPD GO	OLF2_APILI	Olfactory receptor-like protein HbT2 (Fragment)	0.02	-	nuc	2 *	Membrane; multi-pass membrane protein (Probable)				87
Q95155 UniProt NPD GO	OLF2_CANFA	Olfactory receptor-like protein OLF2	0.02	-	end	6 *	Membrane; multi-pass membrane protein				311

You are viewing entries 84701 to 84750 of 98716. You can see more proteins by changing the limits in the form at the top of this page, or click here for the next page of proteins .

If you find NucPred useful, please cite this paper:

NucPred - Predicting Nuclear Localization of Proteins. Brameier M, Krings A, Maccallum RM. Bioinformatics, 2007. PubMed id: 17332022

The authors also look forward to your comments and suggestions.

What does the NucPred score mean?

You have to decide on a NucPred score threshold. Sequences which score greater than or equal to this threshold are predicted to spend some time in the nucleus. Higher thresholds yield fewer predicted nuclear proteins, but these predictions are more accurate (you can have higher confidence in them). The table below gives more details of the performance of NucPred estimated using the sequences it was trained on (by cross-validation). Another benchmark is available in the Bioinformatics 2007 paper.

NucPred score threshold	Specificity	Sensitivity
see above	fraction of proteins predicted to be nuclear that actually are nuclear	fraction of true nuclear proteins that are predicted (coverage)
0.10	0.45	0.88
0.20	0.52	0.83
0.30	0.57	0.77
0.40	0.63	0.69
0.50	0.70	0.62
0.60	0.71	0.53
0.70	0.81	0.44
0.80	0.84	0.32
0.90	0.88	0.21
1.00	1.00	0.02

Sequences which score >= 0.8 with NucPred and which are predicted by PredictNLS to contain an NLS have been shown to be 93% correct with a coverage of 16%. (PredictNLS by itself is 87% correct with 26% coverage on the same data.)

Go back to the NucPred Home Page.