NucPred on Proteomes

Authors: Andrea Krings, Amine Heddad, Markus Brameier and Bob MacCallum, Stockholm Bioinformatics Center, Stockholm University, Sweden.

NucPred - predictions for eukaryotic proteomes

Species:

Note: All filters/tests are combined with AND unless otherwise stated

Show only the proteins with links to database(s):
OMIM - human disease genes
PDB - protein 3D structure
( AND OR combination )

Annotation filters (can be slow! - Perl regexps allowed: e.g. nucleus|nucleolus)

UniProt ID (e.g. "PK3B_")
UniProt description (e.g. "kinase")
UniProt subcellular location
AND
UniProt GO component
AND
AND the
AND the

Only show proteins where the PredictNLS prediction is:

positive
negative

Only show proteins where the PSORT II predicted location

is is not

Click here: to filter by NucPred score

exclude all transmembrane proteins predicted by TMHMM
don't exclude lone N-terminal predicted transmembrane helices
(these could be signal peptides)

export all ACs and IDs as text file

Show proteins (ordered by NucPred score ) from to (currently 98716 matches)

You can bookmark/save your search criteria with this link. You can also start again with default settings.

UniProt accession	UniProt ID	UniProt description	NucPred score	Predict- NLS	PSORT II	TMHMM #helices	UniProt annotation for subcellular location	Uniprot GO cellular component	OMIM	PDB	sequence length
P83867 UniProt NPD GO	OCE3_LEPOE	Ocellatin-3	0.00	-	cyt	0	Secreted protein				21
Q00680 UniProt NPD GO	POX18_CANMA	Oleate-induced peroxisomal protein POX18 (Lipid-transfer protein) (PXP-18)	0.00	-	cyt	0	Peroxisome				126
P22009 UniProt NPD GO	POX18_CANTR	Oleate-induced peroxisomal protein POX18 (Lipid-transfer protein) (PXP-18)	0.00	-	cyt	0	Peroxisome				126
Q96543 UniProt NPD GO	OLE16_BROSE	Oleosin 16 kDa	0.00	-	end	2	Surface of oil bodies. Oleosins exist at a monolayer lipid/water interface (By similarity)				167
Q42980 UniProt NPD GO	OLEO1_ORYSA	Oleosin 16 kDa (OSE701)	0.00	-	end	2 *	Surface of oil bodies. Oleosins exist at a monolayer lipid/water interface				148
P06910 UniProt NPD GO	OLFA_RANPI	Olfactory protein precursor	0.00	-	exc	0					177
Q8VGS3 UniProt NPD GO	O1019_MOUSE	Olfactory receptor 1019 (Olfactory receptor 180-1)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				310
Q8VFK7 UniProt NPD GO	O1020_MOUSE	Olfactory receptor 1020 (Olfactory receptor 201-2)	0.00	-	end	6 *	Membrane; multi-pass membrane protein				317
Q8NGN7 UniProt NPD GO	O10D4_HUMAN	Olfactory receptor 10D4	0.00	-	end	7 *	Membrane; multi-pass membrane protein				298
Q8NGN6 UniProt NPD GO	O10G7_HUMAN	Olfactory receptor 10G7	0.00	-	end	7 *	Membrane; multi-pass membrane protein				311
Q8NGN5 UniProt NPD GO	O10G8_HUMAN	Olfactory receptor 10G8 (Olfactory receptor OR11-282)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				311
O60404 UniProt NPD GO	O10H3_HUMAN	Olfactory receptor 10H3	0.00	-	end	7 *	Membrane; multi-pass membrane protein				316
Q8NGA6 UniProt NPD GO	O10H5_HUMAN	Olfactory receptor 10H5	0.00	-	end	7 *	Membrane; multi-pass membrane protein				315
Q8NGR1 UniProt NPD GO	O13A1_HUMAN	Olfactory receptor 13A1 (Olfactory receptor OR10-3)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				308
Q60886 UniProt NPD GO	OL147_MOUSE	Olfactory receptor 147 (Olfactory receptor 7E) (Olfactory receptor 164-1) (Odorant receptor M3)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				317
P23267 UniProt NPD GO	OL287_RAT	Olfactory receptor 287 (Olfactory receptor-like protein F6)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				311
P59922 UniProt NPD GO	OR2B8_HUMAN	Olfactory receptor 2B8 (Hs6M1-29P)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				312
Q7Z3T1 UniProt NPD GO	OR2W3_HUMAN	Olfactory receptor 2W3 (Olfactory receptor OR1-49)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				314
Q8VG43 UniProt NPD GO	OL472_MOUSE	Olfactory receptor 472 (Olfactory receptor 204-5)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				310
Q8VG44 UniProt NPD GO	OL473_MOUSE	Olfactory receptor 473 (Olfactory receptor 204-4)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				310
Q8VFC9 UniProt NPD GO	OL474_MOUSE	Olfactory receptor 474 (Olfactory receptor 204-20)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				310
Q8VGI4 UniProt NPD GO	OL476_MOUSE	Olfactory receptor 476 (Olfactory receptor 204-3)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				310
Q8VGI6 UniProt NPD GO	OL477_MOUSE	Olfactory receptor 477 (Olfactory receptor 204-1)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				310
Q8VEZ0 UniProt NPD GO	OL480_MOUSE	Olfactory receptor 480 (Olfactory receptor 204-32) (Odorant receptor S25)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				312
Q8VGI5 UniProt NPD GO	OL481_MOUSE	Olfactory receptor 481 (Olfactory receptor 204-2)	0.00	-	end	6 *	Membrane; multi-pass membrane protein				312
Q8VFD3 UniProt NPD GO	OL484_MOUSE	Olfactory receptor 484 (Olfactory receptor 204-16)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				321
Q8VG06 UniProt NPD GO	OL491_MOUSE	Olfactory receptor 491 (Olfactory receptor 204-11)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				310
Q8NH83 UniProt NPD GO	OR4A5_HUMAN	Olfactory receptor 4A5 (Olfactory receptor OR11-111)	0.00	-	end	6 *	Membrane; multi-pass membrane protein				315
Q8NGF8 UniProt NPD GO	OR4B1_HUMAN	Olfactory receptor 4B1 (OST208) (Olfactory receptor OR11-106)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				309
Q8NGM1 UniProt NPD GO	OR4CF_HUMAN	Olfactory receptor 4C15 (Olfactory receptor OR11-127) (Olfactory receptor OR11-134)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				316
Q8NH21 UniProt NPD GO	OR4F5_HUMAN	Olfactory receptor 4F5	0.00	-	end	7 *	Membrane; multi-pass membrane protein				305
Q8NH43 UniProt NPD GO	OR4L1_HUMAN	Olfactory receptor 4L1 (Olfactory receptor OR14-28)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				312
Q8VG42 UniProt NPD GO	OL508_MOUSE	Olfactory receptor 508 (Olfactory receptor 204-6)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				310
Q8VEW6 UniProt NPD GO	OL510_MOUSE	Olfactory receptor 510 (Olfactory receptor 204-34)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				314
Q8NH64 UniProt NPD GO	O51A7_HUMAN	Olfactory receptor 51A7	0.00	-	end	7 *	Membrane; multi-pass membrane protein				312
Q9Y5P1 UniProt NPD GO	O51B2_HUMAN	Olfactory receptor 51B2 (Odorant receptor HOR5'beta3)	0.00	-	end	7 *	Membrane; multi-pass membrane protein	integral to membrane [NAS]			312
Q9H339 UniProt NPD GO	O51B5_HUMAN	Olfactory receptor 51B5 (Odorant receptor HOR5'beta5) (Olfactory receptor OR11-37)	0.00	-	end	7 *	Membrane; multi-pass membrane protein	integral to membrane [NAS]			312
Q9H340 UniProt NPD GO	O51B6_HUMAN	Olfactory receptor 51B5 (Odorant receptor HOR5'beta6)	0.00	-	end	7 *	Membrane; multi-pass membrane protein	integral to membrane [NAS]			312
Q8NGF3 UniProt NPD GO	O51D1_HUMAN	Olfactory receptor 51D1 (Olfactory receptor OR11-14)	0.00	-	end	8 *	Membrane; multi-pass membrane protein				324
Q8NGK1 UniProt NPD GO	O51G1_HUMAN	Olfactory receptor 51G1	0.00	-	end	5 *	Membrane; multi-pass membrane protein				321
Q8NGK0 UniProt NPD GO	O51G2_HUMAN	Olfactory receptor 51G2	0.00	-	end	7 *	Membrane; multi-pass membrane protein				314
Q8NH63 UniProt NPD GO	O51H1_HUMAN	Olfactory receptor 51H1	0.00	-	end	7 *	Membrane; multi-pass membrane protein				302
Q9H343 UniProt NPD GO	O51I1_HUMAN	Olfactory receptor 51I1 (Odorant receptor HOR5'beta11) (Olfactory receptor OR11-39)	0.00	-	end	7 *	Membrane; multi-pass membrane protein	integral to membrane [NAS]			314
Q9H2C5 UniProt NPD GO	O52A5_HUMAN	Olfactory receptor 52A5 (Odorant receptor HOR3'beta5) (Olfactory receptor OR11-33)	0.00	-	end	7 *	Membrane; multi-pass membrane protein	integral to membrane [NAS]			316
Q9H346 UniProt NPD GO	O52D1_HUMAN	Olfactory receptor 52D1 (Odorant receptor HOR5'beta14) (Olfactory receptor OR11-43)	0.00	-	end	8 *	Membrane; multi-pass membrane protein	integral to membrane [NAS]			318
Q8NGJ3 UniProt NPD GO	O52E1_HUMAN	Olfactory receptor 52E1	0.00	-	end	7 *	Membrane; multi-pass membrane protein				308
Q8NH55 UniProt NPD GO	O52E5_HUMAN	Olfactory receptor 52E5	0.00	-	end	7 *	Membrane; multi-pass membrane protein				315
Q96RD3 UniProt NPD GO	O52E6_HUMAN	Olfactory receptor 52E6	0.00	-	end	7 *	Membrane; multi-pass membrane protein				313
Q6IFG1 UniProt NPD GO	O52E8_HUMAN	Olfactory receptor 52E8 (Olfactory receptor OR11-54)	0.00	-	end	7 *	Membrane; multi-pass membrane protein				313
Q8NGK6 UniProt NPD GO	O52I1_HUMAN	Olfactory receptor 52I1	0.00	-	end	7 *	Membrane; multi-pass membrane protein				324

You are viewing entries 96101 to 96150 of 98716. You can see more proteins by changing the limits in the form at the top of this page, or click here for the next page of proteins .

If you find NucPred useful, please cite this paper:

NucPred - Predicting Nuclear Localization of Proteins. Brameier M, Krings A, Maccallum RM. Bioinformatics, 2007. PubMed id: 17332022

The authors also look forward to your comments and suggestions.

What does the NucPred score mean?

You have to decide on a NucPred score threshold. Sequences which score greater than or equal to this threshold are predicted to spend some time in the nucleus. Higher thresholds yield fewer predicted nuclear proteins, but these predictions are more accurate (you can have higher confidence in them). The table below gives more details of the performance of NucPred estimated using the sequences it was trained on (by cross-validation). Another benchmark is available in the Bioinformatics 2007 paper.

NucPred score threshold	Specificity	Sensitivity
see above	fraction of proteins predicted to be nuclear that actually are nuclear	fraction of true nuclear proteins that are predicted (coverage)
0.10	0.45	0.88
0.20	0.52	0.83
0.30	0.57	0.77
0.40	0.63	0.69
0.50	0.70	0.62
0.60	0.71	0.53
0.70	0.81	0.44
0.80	0.84	0.32
0.90	0.88	0.21
1.00	1.00	0.02

Sequences which score >= 0.8 with NucPred and which are predicted by PredictNLS to contain an NLS have been shown to be 93% correct with a coverage of 16%. (PredictNLS by itself is 87% correct with 26% coverage on the same data.)

Go back to the NucPred Home Page.