NucPred on Proteomes

Authors: Andrea Krings, Amine Heddad, Markus Brameier and Bob MacCallum, Stockholm Bioinformatics Center, Stockholm University, Sweden.

NucPred - predictions for eukaryotic proteomes

Species:

Note: All filters/tests are combined with AND unless otherwise stated

Show only the proteins with links to database(s):
OMIM - human disease genes
PDB - protein 3D structure
( AND OR combination )

Annotation filters (can be slow! - Perl regexps allowed: e.g. nucleus|nucleolus)

UniProt ID (e.g. "PK3B_")
UniProt description (e.g. "kinase")
UniProt subcellular location
AND
UniProt GO component
AND
AND the
AND the

Only show proteins where the PredictNLS prediction is:

positive
negative

Only show proteins where the PSORT II predicted location

is is not

Click here: to filter by NucPred score

exclude all transmembrane proteins predicted by TMHMM
don't exclude lone N-terminal predicted transmembrane helices
(these could be signal peptides)

export all ACs and IDs as text file

Show proteins (ordered by NucPred score ) from to (currently 94 matches)

You can bookmark/save your search criteria with this link. You can also start again with default settings.

UniProt accession	UniProt ID	UniProt description	NucPred score	Predict- NLS	PSORT II	TMHMM #helices	UniProt annotation for subcellular location	Uniprot GO cellular component	OMIM	PDB	sequence length
P55196 UniProt NPD GO	AFAD_HUMAN	Afadin (Protein AF-6)	1.00	+	nuc	0	Cell membrane; cell-cell junction; adherens junction. Not found at cell-matrix AJs	intercellular junction [TAS]	159559	1XZ9	1816
Q8WXX7 UniProt NPD GO	AUTS2_HUMAN	Autism susceptibility gene 2 protein	1.00	+	nuc	0			607270		1259
Q14004 UniProt NPD GO	CD2L5_HUMAN	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2-related protein kinase 5) (Cholines ...	1.00	+	nuc	0			603309		1512
Q9Y6V0 UniProt NPD GO	PCLO_HUMAN	Protein piccolo (Aczonin)	1.00	+	nuc	0	Concentrated at the presynaptic side of synaptic junctions (By similarity)	cytoskeleton [NAS] synapse [ISS]	604918	1UJD	5183
Q9UQ26 UniProt NPD GO	RIMS2_HUMAN	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2)	1.00	+	nuc	0			606630	1WFG	1411
Q9BXT5 UniProt NPD GO	TEX15_HUMAN	Testis-expressed sequence 15 protein	1.00	+	nuc	0			605795		2789
Q9Y2D5 UniProt NPD GO	AKAP2_HUMAN	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2)	0.99	+	nuc	0			604582		1103
Q9UIF8 UniProt NPD GO	BAZ2B_HUMAN	Bromodomain adjacent to zinc finger domain 2B (hWALp4)	0.99	+	nuc	0			605683		1972
P15924 UniProt NPD GO	DESP_HUMAN	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)	0.99	+	nuc	0	Innermost portion of the desmosomal plaque	cornified envelope [IDA]	125647	1LM7	2871
Q9NZM3 UniProt NPD GO	ITSN2_HUMAN	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein)	0.99	+	nuc	0	Cytoplasm		604464	1UHF	1696
Q7Z4S6 UniProt NPD GO	KI21A_HUMAN	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen)	0.99	+	nuc	0			608283		1674
O75037 UniProt NPD GO	KI21B_HUMAN	Kinesin family member 21B	0.99	+	nuc	0	Cytoplasm (By similarity)		608322		1637
Q49MG5 UniProt NPD GO	MAP9_HUMAN	Microtubule-associated protein 9 (Aster-associated protein)	0.99	+	nuc	0	Cytoplasm. Localizes to microtubules in interphase, associates with the mitotic spindle during mitos ...		610070		647
P30414 UniProt NPD GO	NKTR_HUMAN	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein)	0.99	+	nuc	0	Membrane; peripheral membrane protein. Attached to the membrane via its N-terminus		161565		1462
O60879 UniProt NPD GO	DIAP2_HUMAN	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2)	0.99	+	nuc	0	Isoform 3: Cytoplasm; cytosol. Isoform 3: Endosome; early endosome. Isoform 3 is cytosolic but when ...		300511		1101
Q86UR5 UniProt NPD GO	RIMS1_HUMAN	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1)	0.99	+	nuc	0		presynaptic membrane [NAS]	603649	2CSS	1692
Q9BXU7 UniProt NPD GO	UBP26_HUMAN	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specif ...	0.99	+	nuc	0			300309		913
Q13227 UniProt NPD GO	GPS2_HUMAN	G protein pathway suppressor 2 (Protein GPS2)	0.98	+	nuc	0			601935		327
O14782 UniProt NPD GO	KIF3C_HUMAN	Kinesin-like protein KIF3C	0.98	+	nuc	0		kinesin complex [TAS]	602845		793
O95819 UniProt NPD GO	M4K4_HUMAN	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase ...	0.98	+	nuc	0			604666		1239
Q96PV0 UniProt NPD GO	SYGP1_HUMAN	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) ...	0.98	+	nuc	0			603384		1328
Q07890 UniProt NPD GO	SOS2_HUMAN	Son of sevenless homolog 2 (SOS-2)	0.98	+	nuc	0			601247		1332
O14617 UniProt NPD GO	AP3D1_HUMAN	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) ( ...	0.97	+	nuc	0		Golgi apparatus [TAS]	607246		1153
Q8N302 UniProt NPD GO	AGGF1_HUMAN	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (Vasculogenesis gene on 5q ...	0.97	+	nuc	0	Cytoplasm. Secreted protein. Cytoplasmic in microvascular endothelial cells. Upon angiogenesis, when ...	cytoplasm [IDA] extracellular region [IDA] perinuclear region [IDA]	608464		714
Q9BXF3 UniProt NPD GO	CECR2_HUMAN	Cat eye syndrome critical region protein 2	0.97	+	nuc	0			607576		1484
Q96QZ7 UniProt NPD GO	MAGI1_HUMAN	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protei ...	0.97	+	nuc	0	Cell membrane; cell-cell junction; tight junction; peripheral membrane protein. Localizes to epithel ...	intercellular junction [TAS] plasma membrane [TAS]	602625		1491
Q8NEM0 UniProt NPD GO	MCPH1_HUMAN	Microcephalin	0.97	+	nuc	0	Centrosome		607117		835
Q8NEV4 UniProt NPD GO	MYO3A_HUMAN	Myosin IIIA (EC 2.7.11.1)	0.97	+	nuc	0			607101		1616
Q9UM54 UniProt NPD GO	MYO6_HUMAN	Myosin-6 (Myosin VI)	0.97	+	nuc	0		unconventional myosin [TAS]	607821		1285
Q5VT25 UniProt NPD GO	MRCKA_HUMAN	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (Myoto ...	0.97	+	nuc	0	Cytoplasm (By similarity). Displays a dispersed punctate distribution and concentrates along the cel ...	intercellular junction [ISS] leading edge [ISS]	603412		1732
Q9NQU5 UniProt NPD GO	PAK6_HUMAN	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5)	0.97	+	nuc	0			608110	2C30	681
P24588 UniProt NPD GO	AKAP5_HUMAN	A-kinase anchor protein 5 (A-kinase anchor protein 79 kDa) (AKAP 79) (cAMP-dependent protein kinase ...	0.96	+	nuc	0	Membrane. Associated with particulate fractions	plasma membrane [NAS]	604688		427
Q12955 UniProt NPD GO	ANK3_HUMAN	Ankyrin-3 (ANK-3) (Ankyrin-G)	0.96	+	nuc	0			600465		4377
Q05682 UniProt NPD GO	CALD1_HUMAN	Caldesmon (CDM)	0.96	+	nuc	0	On thin filaments in smooth muscle and on stress fibers in fibroblasts (nonmuscle) (By similarity)	cytoskeleton [TAS]	114213		793
Q9UL16 UniProt NPD GO	CCD19_HUMAN	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium-specific protein 1)	0.96	+	nuc	0		soluble fraction [TAS]	605152		386
Q8N157 UniProt NPD GO	AHI1_HUMAN	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1)	0.96	+	nuc	0			608894		1196
P13535 UniProt NPD GO	MYH8_HUMAN	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC-perinatal)	0.96	+	nuc	0	Thick filaments of the myofibrils	muscle myosin [TAS]	608837		1937
Q9UPQ7 UniProt NPD GO	PZRN3_HUMAN	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic dom ...	0.96	+	nuc	0			609729	1WH1	1066
O75167 UniProt NPD GO	PHAR2_HUMAN	Phosphatase and actin regulator 2	0.96	+	nuc	0			608724		634
O94851 UniProt NPD GO	MICA2_HUMAN	Protein MICAL-2	0.96	+	nuc	0	Cytoplasm (By similarity)		608881		1124
Q01082 UniProt NPD GO	SPTB2_HUMAN	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta ...	0.96	+	nuc	0		spectrin [TAS]	182790	1BKR	2364
Q07283 UniProt NPD GO	TRHY_HUMAN	Trichohyalin	0.96	+	nuc	0		cytoskeleton [NAS]	190370		1898
Q01970 UniProt NPD GO	PLCB3_HUMAN	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide pho ...	0.95	+	nuc	0	Membrane; peripheral membrane protein		600230		1234
Q01484 UniProt NPD GO	ANK2_HUMAN	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid)	0.95	+	nuc	0			600919		3924
Q9H8V3 UniProt NPD GO	ECT2_HUMAN	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene)	0.95	+	nuc	0			600586		883
Q14152 UniProt NPD GO	IF3A_HUMAN	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p1 ...	0.95	+	nuc	0	Cytoplasm	eukaryotic translation initiation factor 3 ... [TAS]	602039		1382
Q15811 UniProt NPD GO	ITSN1_HUMAN	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)	0.95	+	nuc	0	Intracytoplasmic membrane (By similarity). Synaptosome (By similarity). Enriched in synaptosomes (By ...		602442	1KI1	1721
P11055 UniProt NPD GO	MYH3_HUMAN	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE)	0.95	+	nuc	0	Thick filaments of the myofibrils		160720		1940
P12882 UniProt NPD GO	MYH1_HUMAN	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d)	0.95	+	nuc	0	Thick filaments of the myofibrils		160730		1939
Q9Y623 UniProt NPD GO	MYH4_HUMAN	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb)	0.95	+	nuc	0	Thick filaments of the myofibrils		160742		1939
Q9GZR1 UniProt NPD GO	SENP6_HUMAN	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific pr ...	0.95	+	nuc	0	Cytoplasm		605003		1112
P53804 UniProt NPD GO	TTC3_HUMAN	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D)	0.95	+	nuc	0			602259		2025
Q15642 UniProt NPD GO	CIP4_HUMAN	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10)	0.94	+	nuc	0		cytoplasm [NAS]	604504	2CT4	545
P35663 UniProt NPD GO	CYLC1_HUMAN	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I)	0.94	+	nuc	0	Calyx. Sperm head cytoskeletal structure	acrosomal matrix [IDA] cytoskeleton [NAS]	603121		651
P20585 UniProt NPD GO	MSH3_HUMAN	DNA mismatch repair protein Msh3 (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP ...	0.94	+	nuc	0			608089		1137
Q9Y4D1 UniProt NPD GO	DAAM1_HUMAN	Disheveled-associated activator of morphogenesis 1	0.94	+	nuc	0			606626		1078
Q12929 UniProt NPD GO	EPS8_HUMAN	Epidermal growth factor receptor kinase substrate 8	0.94	+	nuc	0			600206		822
Q8N4C8 UniProt NPD GO	MINK1_HUMAN	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAP ...	0.94	+	nuc	0			609426		1332
Q9UKX2 UniProt NPD GO	MYH2_HUMAN	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa)	0.94	+	nuc	0	Thick filaments of the myofibrils	muscle myosin [TAS]	160740		1941
Q9UKN7 UniProt NPD GO	MYO15_HUMAN	Myosin-15 (Myosin XV) (Unconventional myosin-15)	0.94	+	nuc	0	Cytoplasm		602666		3530
Q13402 UniProt NPD GO	MYO7A_HUMAN	Myosin-7A (Myosin VIIa)	0.94	+	nuc	0	Cytoplasm (Probable). In the photoreceptor cells, mainly localized in the inner and base of outer se ...		601317		2215
O60890 UniProt NPD GO	OPHN1_HUMAN	Oligophrenin 1	0.94	+	nuc	0			300486		802
Q9H257 UniProt NPD GO	CARD9_HUMAN	Caspase recruitment domain-containing protein 9 (hCARD9)	0.93	+	nuc	0	Cytoplasm		607212		536
Q9NVF7 UniProt NPD GO	FBX28_HUMAN	F-box only protein 28	0.93	+	nuc	0			609100		368
Q99689 UniProt NPD GO	FEZ1_HUMAN	Fasciculation and elongation protein zeta 1 (Zygin-1) (Zygin I)	0.93	+	nuc	0	Cytoplasm (By similarity). Cell membrane (By similarity). Translocated from the plasma membrane to t ...		604825		392
Q9Y496 UniProt NPD GO	KIF3A_HUMAN	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A)	0.93	+	nuc	0			604683		702
Q86UL8 UniProt NPD GO	MAGI2_HUMAN	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated gu ...	0.93	+	nuc	0	Synaptosome; peripheral membrane protein (By similarity). Membrane-associated in synaptosomes (By si ...		606382	1WFV	1455
P12883 UniProt NPD GO	MYH7_HUMAN	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta)	0.93	+	nuc	0	Thick filaments of the myofibrils	muscle myosin [TAS]	115200	1IK2	1935
P35580 UniProt NPD GO	MYH10_HUMAN	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC ...	0.93	+	nuc	0		myosin [NAS]	160776		1976
Q9H4L5 UniProt NPD GO	OSBL3_HUMAN	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3)	0.93	+	nuc	0			606732		887
Q9C0D0 UniProt NPD GO	PHAR1_HUMAN	Phosphatase and actin regulator 1	0.93	+	nuc	0	Cytoplasm (By similarity). Enriched at synapses (By similarity)		608723		580
O15066 UniProt NPD GO	KIF3B_HUMAN	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048)	0.92	+	nuc	0		plus-end kinesin complex [TAS]	603754		747
Q13164 UniProt NPD GO	MK07_HUMAN	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) ...	0.92	+	nuc	0			602521		815
P13533 UniProt NPD GO	MYH6_HUMAN	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha)	0.92	+	nuc	0	Thick filaments of the myofibrils	muscle myosin [TAS]	160710		1939
Q92954 UniProt NPD GO	PRG4_HUMAN	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglyca ...	0.92	+	nuc	0	Secreted protein		604283		1404
Q15311 UniProt NPD GO	RBP1_HUMAN	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitr ...	0.92	+	nuc	0	Membrane; peripheral membrane protein	membrane [IDA]	605801		654
P54792 UniProt NPD GO	DVL1L_HUMAN	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled-1-like) (DSH homolog 1-like)	0.92	+	nuc	0	Cytoplasm (Potential)	cytoplasm [NAS]	601225		670
O00295 UniProt NPD GO	TULP2_HUMAN	Tubby-related protein 2 (Tubby-like protein 2)	0.92	+	nuc	0			602309		520
P15692 UniProt NPD GO	VEGFA_HUMAN	Vascular endothelial growth factor A precursor (VEGF-A) (Vascular permeability factor) (VPF)	0.92	+	nuc	0	Secreted protein. VEGF121 is acidic and freely secreted. VEGF165 is more basic, has heparin-binding ...	extracellular matrix (sensu Metazoa) [NAS] extracellular space [IDA]	192240	2VPF	232
Q9UPY6 UniProt NPD GO	WASF3_HUMAN	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Ve ...	0.92	+	nuc	0	Cytoplasm		605068		502
Q9NRI5 UniProt NPD GO	DISC1_HUMAN	Disrupted in schizophrenia 1 protein	0.91	+	nuc	0	Localizes to neurites (By similarity). Cytoplasm. Localizes to punctate cytoplasmic foci which overl ...		605210		854
P35749 UniProt NPD GO	MYH11_HUMAN	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC)	0.91	+	nuc	0	Thick filaments of the myofibrils	muscle myosin [TAS]	160745		1972
Q12967 UniProt NPD GO	GNDS_HUMAN	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS)	0.91	+	nuc	0			601619	2RGF	914
Q13017 UniProt NPD GO	RHG05_HUMAN	Rho-GTPase-activating protein 5 (p190-B)	0.91	+	nuc	0	Cytoplasm. Membrane; peripheral membrane protein. Also membrane-associated when found in fibrillar p ...	cytoplasm [TAS]	602680		1499
Q9HCB6 UniProt NPD GO	SPON1_HUMAN	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth-promoting factor)	0.91	+	nuc	0	Secreted protein; extracellular space; extracellular matrix (By similarity)		604989		807
Q9NVP1 UniProt NPD GO	DDX18_HUMAN	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) ...	0.90	+	nuc	0			606355		670
P11274 UniProt NPD GO	BCR_HUMAN	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen)	0.90	+	nuc	0			151410	1K1F	1271
Q96L91 UniProt NPD GO	EP400_HUMAN	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino ...	0.90	+	nuc	0			606265		3160
Q9UEY8 UniProt NPD GO	ADDG_HUMAN	Gamma-adducin (Adducin-like protein 70)	0.90	+	nuc	0		membrane [TAS]	601568		706
Q8N3R9 UniProt NPD GO	MPP5_HUMAN	MAGUK p55 subfamily member 5	0.90	+	nuc	0	Cell membrane; peripheral membrane protein. Intracellular membrane; peripheral membrane protein. Loc ...		606958	1Y76	675
Q99569 UniProt NPD GO	PKP4_HUMAN	Plakophilin-4 (p0071)	0.90	+	nuc	0	Cell membrane; cell-cell junction; desmosome. Colocalized with desmoplakin at desmosomal junctional ...	intercellular junction [TAS]	604276		1211
Q9NQ29 UniProt NPD GO	LUC7L_HUMAN	Putative RNA-binding protein Luc7-like 1 (SR+89) (Putative SR protein LUC7B1)	0.90	+	nuc	0			607782		371
Q96J92 UniProt NPD GO	WNK4_HUMAN	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase ...	0.90	+	nuc	0	Cell membrane; cell-cell junction; tight junction (By similarity). Present exclusively in intercellu ...	tight junction [ISS]	601844		1243
O00294 UniProt NPD GO	TULP1_HUMAN	Tubby-related protein 1 (Tubby-like protein 1)	0.90	+	nuc	0			600132	2FIM	542

If you find NucPred useful, please cite this paper:

NucPred - Predicting Nuclear Localization of Proteins. Brameier M, Krings A, Maccallum RM. Bioinformatics, 2007. PubMed id: 17332022

The authors also look forward to your comments and suggestions.

What does the NucPred score mean?

You have to decide on a NucPred score threshold. Sequences which score greater than or equal to this threshold are predicted to spend some time in the nucleus. Higher thresholds yield fewer predicted nuclear proteins, but these predictions are more accurate (you can have higher confidence in them). The table below gives more details of the performance of NucPred estimated using the sequences it was trained on (by cross-validation). Another benchmark is available in the Bioinformatics 2007 paper.

NucPred score threshold	Specificity	Sensitivity
see above	fraction of proteins predicted to be nuclear that actually are nuclear	fraction of true nuclear proteins that are predicted (coverage)
0.10	0.45	0.88
0.20	0.52	0.83
0.30	0.57	0.77
0.40	0.63	0.69
0.50	0.70	0.62
0.60	0.71	0.53
0.70	0.81	0.44
0.80	0.84	0.32
0.90	0.88	0.21
1.00	1.00	0.02

Sequences which score >= 0.8 with NucPred and which are predicted by PredictNLS to contain an NLS have been shown to be 93% correct with a coverage of 16%. (PredictNLS by itself is 87% correct with 26% coverage on the same data.)

Go back to the NucPred Home Page.